Friede Springer Cardiovascular Prevention Center @Charité

Our mission

We develop practicable precision prevention for a heart-healthy life:

For all citizens, professionals, healthcare systems and decision-makers
With innovative, evidence-based concepts
a holistic approach across the life span
For a lasting positive impact to create a healthier society, health system and economy

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In networked research modules, we investigate the development of cardiovascular diseases in a holistic and multidisciplinary manner.

Our research:
Comprehensive. Measurable. Transformative.

Cardiovascular diseases develop over decades. The various risk factors work together in ways that make their combined effects stronger and affect each person’s health differently. We therefore conduct comprehensive research into potential risks at the earliest stage, measured through innovative procedures, state-of-the-art technology, and valid scientific methods—long before a heart attack or stroke occurs. Our team examines individual measures within various research modules through longitudinal observational and intervention studies to determine who benefits most. These findings lead to personalized therapies that are practical for everyday life and help maintain heart and vascular health for the long term.

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Heart Health Study

The study is the “heart” of our mission. Up to 5,000 participants between the ages of 18 and 70 will undergo comprehensive examinations to identify risk factors even before the first symptoms appear.

By agreeing to take part in the Heart Health Study as a volunteer, you are helping our research team to gain new insights into the prevention of cardiovascular disease. In the long term, we would like to invite you repeatedly at regular intervals and accompany you scientifically.

Join our mission to prevent cardiovascular diseases like heart attacks and strokes through this study.

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Support our research

Become a participant!

Our Heart Health Study is in the pilot phase through the end of 2026. We would be delighted if you would add your name to the waiting list now for the main study, which will begin in the spring of 2027. We will contact you by phone well in advance of the study’s start date. Thank you very much.

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Our team

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News

Heart failure: How physical exertion reveals hidden changes in the body

Physical exertion affects people with heart failure differently than healthy individuals. Our study shows how exercise can reveal unfavorable metabolic and inflammatory patterns—which is important for earlier risk assessment.

Mental stress after a heart attack: results of the PsyCardio study

The PsyCardio study, which was conducted in the Psychology and Cognition research module, has now been published in the journal BMC Cardiovascular Disorders.

Advances in targeted nucleic acid therapies for the prevention of cardiovascular diseases

In contrast to conventional drugs, nucleic acid-based therapies enable targeted intervention at the molecular level.

How physical training affects the cardiovascular system and the immune system in patients with metabolic syndrome.

Analysis of two randomized clinical trials.

New study warns of increased risk of heart disease from xylitol sweetener

A study carried out by Dr. Marco Witkowski during a research stay at the Cleveland Clinic in Ohio/USA provides new insights into the potential health risks of the widely used sweetener xylitol.

TAVI Procedure for Aortic Valve Replacement Compared to the Surgical Method

Prof. Ulf Landmesser, MD, Director of the FRIEDE SPRINGER - Cardiovascular Prevention Center, summarizes findings from the PARTNER 3 study in an editorial for the New England Journal of Medicine (NEJM). The editorial underscores the urgent need for novel strategies to prevent the progression of valvular heart diseases, particularly aortic valve stenosis, a prevalent condition.

No results found.

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Friede Springer

Cardiovascular Prevention
Center @Charité